› 1zy6

Solid-state NMR

Membrane-bound dimer structure of Protegrin-1 (PG-1), a beta-Hairpin Antimicrobial Peptide in Lipid Bilayers from Rotational-Echo Double-Resonance Solid-State NMR

Released:
DOI: 10.2210/pdb1zy6/pdb
PDB entry 1zy6 coloured by chain, front view.
PDB entry 1zy6 coloured by chain, side view.
PDB entry 1zy6 coloured by chain, top view.
Source organism: Sus scrofa
Primary publication:
Membrane-bound dimer structure of a beta-hairpin antimicrobial peptide from rotational-echo double-resonance solid-state NMR.
Mani R, Tang M, Wu X, Buffy JJ, Waring AJ, Sherman MA, Hong M
Biochemistry 45 8341-9 (2006)
PMID: 16819833

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152227 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protegrin-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 19 amino acids
Theoretical weight: 2.16 KDa
Source organism: Sus scrofa
Expression system: Not provided
UniProt:
  • Canonical: P32194 (Residues: 131-148; Coverage: 15%)
Gene name: NPG1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: Distance geometry; Simulated annealing
Expression system: Not provided

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Citations

11 review citations

Fluorinated amino acids: compatibility with native protein structures and effects on protein-protein interactions.
Salwiczek et al. (2012)
10 more

10 mentions without citation

Overcoming Methicillin-Resistance Staphylococcus aureus (MRSA) Using Antimicrobial Peptides-Silver Nanoparticles.
Masimen et al. (2022)
9 more