1zq3 Summary


NMR Solution Structure of the Bicoid Homeodomain Bound to the Consensus DNA Binding Site TAATCC

The structure was published by Baird-Titus, J.M., Clark-Baldwin, K., Dave, V., Caperelli, C.A., Ma, J., and Rance, M., in 2006 in a paper entitled "The solution structure of the native K50 Bicoid homeodomain bound to the consensus TAATCC DNA-binding site." (abstract).

The structure was determined using NMR spectroscopy and deposited in 2005.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 3 biomacromolecules, namely 5'-D(*GP*CP*TP*CP*TP*AP*AP*TP*CP*CP*CP*CP*G)-3', 5'-D(*CP*GP*GP*GP*GP*AP*TP*TP*AP*GP*AP*GP*C)-3', and Homeotic bicoid protein.

The molecule most likely forms heterotrimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
P Homeotic bicoid protein P09081 (97-163) (BCD_DROME)search Drosophila melanogastersearch < 90% 68 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P09081 (97 - 163) Homeotic bicoid protein Drosophila melanogaster

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
P Homeodomainsearch Homeodomain-likesearch Homeobox domainsearch

Chain ID Molecular function (GO) Biological process (GO)
P (P09081) sequence-specific DNA bindingsearch DNA bindingsearch regulation of transcription, DNA-templatedsearch

Chain InterPro annotation
P Homeobox domainsearch Homeodomain-likesearch Homeobox, conserved sitesearch