Assemblies
Assembly Name:
ERalpha-NCOA2 activated estrogen receptor complex
Multimeric state:
hetero tetramer
Accessible surface area:
20248.91 Å2
Buried surface area:
7142.64 Å2
Dissociation area:
996.97
Å2
Dissociation energy (ΔGdiss):
6.59
kcal/mol
Dissociation entropy (TΔSdiss):
14.29
kcal/mol
Symmetry number:
2
PDBe Complex ID:
PDB-CPX-136928
Macromolecules
Chains: A, B
Length: 257 amino acids
Theoretical weight: 29.53 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Pfam: Ligand-binding domain of nuclear hormone receptor
InterPro:
Length: 257 amino acids
Theoretical weight: 29.53 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P03372 (Residues: 298-554; Coverage: 43%)
Pfam: Ligand-binding domain of nuclear hormone receptor
InterPro:
- Nuclear hormone receptor-like domain superfamily
- Nuclear hormone receptor, ligand-binding domain
- Nuclear hormone receptor