1zfp Summary

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GROWTH FACTOR RECEPTOR BINDING PROTEIN SH2 DOMAIN COMPLEXED WITH A PHOSPHOTYROSYL PENTAPEPTIDE

The structure was published by Rahuel, J., Garcia-Echeverria, C., Furet, P., et al., Fretz, H., Schoepfer, J., and Gay, B., in 1998 in a paper entitled "Structural basis for the high affinity of amino-aromatic SH2 phosphopeptide ligands." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.8 Å and deposited in 1998.

The experimental data on which the structure is based was not deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely GROWTH FACTOR RECEPTOR BINDING PROTEIN and EPIDERMAL GROWTH FACTOR RECEPTOR-DERIVED PEPTIDE.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
E GROWTH FACTOR RECEPTOR BINDING PROTEIN P62993 (56-153) (GRB2_HUMAN)search Homo sapienssearch 100% 98 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P62993 (56 - 153) GROWTH FACTOR RECEPTOR BINDING PROTEIN Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
E (P62993) SH2 domainsearch SHC Adaptor Proteinsearch PF00017: SH2 domainsearch
Chain InterPro annotation
E SH2 domainsearch