Crystal Structure of Human PPAR-gamma Ligand Binding Domain Complexed with an Alpha-Aryloxyphenylacetic Acid Agonist
The structure was published by Shi, G.Q., Dropinski, J.F., McKeever, B.M., et al., Heck, J.V., Moller, D.E., and Jones, B.A., in 2005 in a paper entitled "Design and Synthesis of alpha-Aryloxyphenylacetic Acid Derivatives: A Novel Class of PPAR alpha/gamma Dual Agonists with Potent Antihyperglycemic and Lipid Modulating Activity" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.5 Å and deposited in 2005.
The experimental data on which the structure is based was also deposited.
This PDB entry contains multiple copies of the structure of Peroxisome proliferator activated receptor gamma.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule most likely forms homodimers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: