1ze7 Summary


Zinc-binding domain of Alzheimer's disease amyloid beta-peptide in water solution at pH 6.5

The structure was published by Zirah, S., Kozin, S.A., Mazur, A.K., et al., Segalas-Milazzo, I., Debey, P., and Rebuffat, S., in 2006 in a paper entitled "Structural changes of region 1-16 of the Alzheimer disease amyloid beta-peptide upon zinc binding and in vitro aging." (abstract).

The structure was determined using NMR spectroscopy and deposited in 2005.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of 16-mer from Alzheimer's disease amyloid Protein. This molecule has the UniProt identifier P05067 (A4_HUMAN)search. The sample contained 18 residues which is < 90% of the natural sequence. Out of 18 residues 18 were observed and are deposited in the PDB.

The molecule is most likely monomeric.

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P05067 (672 - 687) 16-mer from Alzheimer's disease amyloid Protein

Chain Sequence family (Pfam)
Chain InterPro annotation