1zbk Summary


Recognition of specific peptide sequences by signalling protein from sheep mammary gland (SPS-40): Crystal structure of the complex of SPS-40 with a peptide Trp-Pro-Trp at 2.9A resolution

A publication describing this structure is not available. The depositing authors are Srivastava, D.B.search; Ethayathulla, A.S.search; Kumar, J.search; Singh, N.search; Somvanshi, R.K.search; Sharma, S.search; Dey, S.search; Singh, T.P.search

This crystal structure was determined using X-ray diffraction at a resolution of 2.9 Å and deposited in 2005.

The experimental data on which the structure is based was not deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely Chitinase-3 like protein 1 and PEPTIDE TRP-PRO-TRP.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms heterodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Chitinase-3 like protein 1 Q6TMG6 (1-360) (CH3L1_SHEEP)search Ovis ariessearch 100% 361 100%
Synthetic Not available 3 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q6TMG6 (1 - 360) Chitinase-3 like protein 1 Ovis aries

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (Q6TMG6) Type II chitinasesearch, Chitinase insertion domainsearch Glycosidasessearch, Chitinase A; domain 3search PF00704: Glycosyl hydrolases family 18search

Chain ID Biological process (GO) Cellular component (GO) Molecular function (GO)
A (Q6TMG6) positive regulation of angiogenesissearch positive regulation of ERK1 and ERK2 cascadesearch response to interleukin-6search inflammatory responsesearch carbohydrate metabolic processsearch response to tumor necrosis factorsearch activation of NF-kappaB-inducing kinase activitysearch positive regulation of peptidyl-threonine phosphorylationsearch positive regulation of protein kinase B signalingsearch chitin catabolic processsearch cellular response to tumor necrosis factorsearch response to mechanical stimulussearch response to interleukin-1search lung developmentsearch apoptotic processsearch interleukin-8 secretionsearch cytoplasmsearch extracellular spacesearch endoplasmic reticulumsearch extracellular regionsearch perinuclear region of cytoplasmsearch carbohydrate bindingsearch chitin bindingsearch chitinase activitysearch hydrolase activity, hydrolyzing O-glycosyl compoundssearch

Chain InterPro annotation
A Glycoside hydrolase, family 18, catalytic domainsearch Chitinase IIsearch Glycoside hydrolase, catalytic domainsearch Glycoside hydrolase superfamilysearch Chitinase-3-like protein 1search Chitinase insertion domainsearch