1zar Summary


Crystal Structure of A.fulgidus Rio2 Kinase Complexed With ADP and Manganese Ions

The structure was published by Laronde-Leblanc, N., Guszczynski, T., Copeland, T., and Wlodawer, A., in 2005 in a paper entitled "Autophosphorylation of Archaeoglobus fulgidus Rio2 and crystal structures of its nucleotide-metal ion complexes." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.75 Å and deposited in 2005.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of Rio2 kinase. This molecule has the UniProt identifier O30245 (RIO2_ARCFU)search. The sample contained 282 residues which is 100% of the natural sequence. Out of 282 residues 265 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Rio2 kinase O30245 (1-282) (RIO2_ARCFU)search Archaeoglobus fulgidus DSM 4304search 100% 282 94%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
O30245 (1 - 282) Rio2 kinase Archaeoglobus fulgidus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (O30245) Rio2 serine protein kinase N-terminal domainsearch, RIO1-like kinasessearch "winged helix" repressor DNA binding domainsearch, Phosphorylase Kinase; domain 1search, Transferase(Phosphotransferase) domain 1search PF01163: RIO1 familysearch, PF09202: Rio2, N-terminalsearch

Chain ID Molecular function (GO) Biological process (GO)
A (O30245) ATP bindingsearch transferase activity, transferring phosphorus-containing groupssearch protein serine/threonine kinase activitysearch catalytic activitysearch protein kinase activitysearch metal ion bindingsearch transferase activitysearch kinase activitysearch nucleotide bindingsearch protein phosphorylationsearch phosphorylationsearch

Chain InterPro annotation
A RIO kinasesearch Tyrosine-protein kinase, active sitesearch Protein kinase-like domainsearch Winged helix-turn-helix DNA-binding domainsearch RIO2 kinase winged helix domain, N-terminalsearch RIO domainsearch