› 1z99

Solution NMR

Solution structure of Crotamine, a myotoxin from Crotalus durissus terrificus

Released:
DOI: 10.2210/pdb1z99/pdb
PDB entry 1z99 coloured by chain, ensemble of 20 models, front view.
PDB entry 1z99 coloured by chain, ensemble of 20 models, side view.
PDB entry 1z99 coloured by chain, ensemble of 20 models, top view.
Source organism: Crotalus durissus terrificus
Primary publication:
Automated NMR structure determination and disulfide bond identification of the myotoxin crotamine from Crotalus durissus terrificus.
Fadel V, Bettendorff P, Herrmann T, de Azevedo WF, Oliveira EB, Yamane T, Wüthrich K
Toxicon 46 759-67 (2005)
PMID: 16185738

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192950 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Crotamine Chain: A
Molecule details ›
Chain: A
Length: 42 amino acids
Theoretical weight: 4.9 KDa
Source organism: Crotalus durissus terrificus
UniProt:
  • Canonical: Q9PWF3 (Residues: 23-64; Coverage: 98%)
Gene names: CRO2, CRT-P1
Sequence domains: Myotoxin, crotamine
Structure domains: Anthopleurin-A

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: OPALp

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Citations

10 review citations

Multispecific myeloid defensins.
Lehrer RI. (2007)
9 more

4 mentions without citation

Cytotoxic and antitumor peptides as novel chemotherapeutics.
Luan et al. (2021)
3 more