1z7h Summary


2.3 Angstrom crystal structure of tetanus neurotoxin light chain

The structure was published by Breidenbach, M.A. and Brunger, A.T., in 2005 in a paper entitled "2.3A Crystal structure of tetanus neurotoxin light chain" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.3 Å and deposited in 2005.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of Tetanus toxin light chain. This molecule has the UniProt identifier P04958 (TETX_CLOTE)search. The sample contained 447 residues which is < 90% of the natural sequence. Out of 447 residues 426 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Tetanus toxin light chain P04958 (1-443) (TETX_CLOTE)search Clostridium tetani E88search < 90% 447 95%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P04958 (1 - 443) Tetanus toxin light chain Clostridium tetani

Chain Structural classification (CATH) Sequence family (Pfam)
A Metalloproteases ("zincins"), catalytic domain likesearch Clostridial neurotoxin zinc proteasesearch

Chain ID Molecular function (GO) Biological process (GO)
A (P04958) metalloendopeptidase activitysearch proteolysissearch pathogenesissearch

Chain InterPro annotation
A Botulinum neurotoxin/Tetanus toxinsearch