1z7c Summary


Crystal Structure of Human Placental Lactogen

The structure was published by Walsh, S.T.R. and Kossiakoff, A.A., in 2006 in a paper entitled "Crystal Structure and Site 1 Binding Energetics of Human Placental Lactogen." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.0 Å and deposited in 2005.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of Chorionic somatomammotropin hormone. This molecule has the UniProt identifier P0DML2 (CSH1_HUMAN)search. The sample contained 191 residues which is 100% of the natural sequence. Out of 191 residues 160 were observed and are deposited in the PDB.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Chorionic somatomammotropin hormone P0DML2 (27-217) (CSH1_HUMAN)search Homo sapienssearch 100% 191 84%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P0DML2 (27 - 217) Chorionic somatomammotropin hormone Homo sapiens

Chain Structural classification (CATH)
A Growth Hormone; Chain: A;search

Chain ID Molecular function (GO) Cellular component (GO)
A (P0DML2) hormone activitysearch extracellular regionsearch

Chain InterPro annotation
A Somatotropin hormonesearch Four-helical cytokine-like, coresearch Four-helical cytokine, coresearch Somatotropin hormone, conserved sitesearch