1z6c Summary


Solution structure of an EGF pair (EGF34) from vitamin K-dependent protein S

The structure was published by Drakenberg, T., Ghasriani, H., Thulin, E., Muranyi, A., Annila, A., and Stenflo, J., in 2005 in a paper entitled "Solution Structure of the Ca(2+)-Binding EGF3-4 Pair from Vitamin K-Dependent Protein S: Identification of an Unusual Fold in EGF3." (abstract).

The structure was determined using NMR spectroscopy and deposited in 2005.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of Vitamin K-dependent protein S. This molecule has the UniProt identifier P07225 (PROS_HUMAN)search. The sample contained 87 residues which is < 90% of the natural sequence. Out of 87 residues 87 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Vitamin K-dependent protein S P07225 (200-286) (PROS_HUMAN)search Homo sapienssearch < 90% 87 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P07225 (200 - 286) Vitamin K-dependent protein S Homo sapiens

Chain Structural classification (CATH) Sequence family (Pfam)
A Lamininsearch Calcium-binding EGF domainsearch

Chain ID Molecular function (GO)
A (P07225) calcium ion bindingsearch

Chain InterPro annotation
A EGF-type aspartate/asparagine hydroxylation sitesearch Epidermal growth factor-like domainsearch EGF-like calcium-binding domainsearch EGF-like, conserved sitesearch EGF-like calcium-binding, conserved sitesearch