1yyh Summary


Crystal structure of the human Notch 1 ankyrin domain

The structure was published by Ehebauer, M.T., Chirgadze, D.Y., Hayward, P., Martinez-Arias, A., and Blundell, T.L., in 2005 in a paper entitled "High-resolution crystal structure of the human Notch 1 ankyrin domain" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.901 Å and deposited in 2005.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of Notch 1, ankyrin domain.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Notch 1, ankyrin domain P46531 (1872-2114) (NOTC1_HUMAN)search Homo sapienssearch < 90% 253 76%
B Notch 1, ankyrin domain P46531 (1872-2114) (NOTC1_HUMAN)search Homo sapienssearch < 90% 253 76%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P46531 (1872 - 2114) Notch 1, ankyrin domain Homo sapiens

Chain Structural classification (CATH) Sequence family (Pfam)
A, B Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeatsearch Ankyrin repeatsearch, Ankyrin repeats (3 copies)search, Ankyrin repeats (many copies)search
Chain InterPro annotation
A, B Ankyrin repeatsearch Ankyrin repeat-containing domainsearch