Crystal Structure of Kinase Pim1 in complex with (3E)-3-[(4-HYDROXYPHENYL)IMINO]-1H-INDOL-2(3H)-ONE
The structure was published by Kumar, A., Mandiyan, V., Suzuki, Y., et al., Artis, D.R., Ibrahim, P., and Bremer, R., in 2005 in a paper entitled "Crystal Structures of Proto-oncogene Kinase Pim1: A Target of Aberrant Somatic Hypermutations in Diffuse Large Cell Lymphoma." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.0 Å and deposited in 2005.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of Proto-oncogene serine/threonine-protein kinase Pim-1. This molecule has the UniProt identifier P11309 (PIM1_HUMAN). The sample contained 293 residues which is < 90% of the natural sequence. Out of 293 residues 274 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule is most likely monomeric.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: