Crystal structure of the Jak3 kinase domain in complex with a staurosporine analogue
The structure was published by Boggon, T.J., Li, Y., Manley, P.W., and Eck, M.J., in 2005 in a paper entitled "Crystal structure of the Jak3 kinase domain in complex with a staurosporine analog" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.55 Å and deposited in 2005.
The experimental data on which the structure is based was not deposited.
The PDB entry contains the structure of Tyrosine-protein kinase JAK3. This molecule has the UniProt identifier P52333 (JAK3_HUMAN). The sample contained 290 residues which is < 90% of the natural sequence. Out of 290 residues 288 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule is most likely monomeric.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: