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EBI PDBe PDBeView

PDBe Entry: 1yml view

Crystal Structure of the CDC25B phosphatase catalytic domain with the active site cysteine in the sulfenic form
Summary
Header HYDROLASE, CELL CYCLEsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 1.7 Å, R-factor: 20.5%, Free R-factor: 20.8%, Spacegroup: P 21 21 21
Released 12/04/2005, deposition: 21/01/2005, last revision: 24/02/2009
Authors Buhrman, G.K.search; Parker, B.search; Sohn, J.search; Rudolph, J.search; Mattos, C.search
Primary citation Structural Mechanism of Oxidative Regulation of the Phosphatase Cdc25B via an Intramolecular Disulfide Bond
BIOCHEMISTRYsearch vol:44, pag:5307-5316 (2005) [PubMed ID 15807524 ]search
Keywords sulfenic Cysteinesearch, HYDROLASEsearch, CELL CYCLEsearch
EC 3.1.3.48 ExPASy BRENDA search (A)
Organism Homo sapiens(human) 9606search(A)
UniProt M-phase inducer phosphatase 2 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25B) P30305search (A)
Solvent A
Related entries 1ym9, 1ymd, 1ymk, 1ys0
Polymers
Id Name Type UniProt Residues Observed
A M-phase inducer phosphatase 2 Protein P30305 (MPIP2_HUMAN)search
 175 97%
Heterogens
Id Name Ligands
A CHLORIDE ION CL search
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