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EBI PDBe PDBeView

PDBe Entry: 1ybg view

MurA inhibited by a derivative of 5-sulfonoxy-anthranilic acid
Summary
Header TRANSFERASEsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 2.6 Å, R-factor: 20.9%, Free R-factor: 25.3%, Spacegroup: P 21 21 21
Released 15/02/2005, deposition: 20/12/2004, last revision: 29/12/2009
Authors Eschenburg, S.search; Priestman, M.A.search; Abdul-Latif, F.A.search; Delachaume, C.search; Fassy, F.search; Schonbrunn, E.search
Primary citation A Novel Inhibitor That Suspends the Induced Fit Mechanism of UDP-N-acetylglucosamine Enolpyruvyl Transferase (MurA).
J.BIOL.CHEM.search vol:280, pag:14070-14075 (2005) [PubMed ID 15701635 ]search
Keywords inside-out alpha-beta barrelsearch, TRANSFERASEsearch
EC 2.5.1.7 ExPASy BRENDA search (A B C D)
Organism Enterobacter cloacae 550search(A B C D)
UniProt UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC 2.5.1.7) (Enoylpyruvate transferase) (UDP-N-acetylglucosamine enolpyruvyl transferase) (EPT) P33038search (A B C D)
Solvent A, B, C, D
Related entries 1naw, 1ejd, 1q3g, 1eyn, 1ejc, 1uae
Polymers
Id Name Type UniProt Residues Observed
A, B, C, D UDP-N-acetylglucosamine 1-carboxyvinyltransferase Protein P33038 (MURA_ENTCL)search
 419 100%
Heterogens
Id Name Ligands
A, B, C, D N-METHYL-N-{2-[(2-NAPHTHYLSULFONYL)AMINO]-5-[(2-NAPHTHYLSULFONYL)OXY]BENZOYL}-L-ASPARTIC ACID TAV search
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