1y7k Summary


NMR structure family of Human Agouti Signalling Protein (80-132: Q115Y, S124Y)

The structure was published by McNulty, J.C., Jackson, P.J., Thompson, D.A., et al., Barsh, G.S., Dawson, P.E., and Millhauser, G.L., in 2005 in a paper entitled "Structures of the agouti signaling protein." (abstract).

The structure was determined using NMR spectroscopy and deposited in 2004.

The experimental data on which the structure is based was not deposited.

The PDB entry contains the structure of Agouti Signaling Protein. This molecule has the UniProt identifier P42127 (ASIP_HUMAN)search. The sample contained 53 residues which is < 90% of the natural sequence. Out of 53 residues 40 were observed and are deposited in the PDB.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Agouti Signaling Protein P42127 (80-132) (ASIP_HUMAN)search Homo sapienssearch < 90% 53 75%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P42127 (80 - 132) Agouti Signaling Protein

Chain Structural classification (CATH) Sequence family (Pfam)
A Agouti Related Protein; Chain Asearch Agouti proteinsearch
Chain InterPro annotation
A Agoutisearch Agouti domainsearch