› › Structure analysis

Crystal structure of PPAR delta complexed with GW2331

X-ray diffraction
2.65Å resolution
PDB entry 1y0s coloured by chain, front view.
PDB entry 1y0s coloured by chain, side view.
PDB entry 1y0s coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1
Download    3D Visualisation
Assembly Name: Peroxisome proliferator-activated receptor delta
hide full assembly name
Multimeric state: monomeric
Accessible surface area: 12572.2 Å2
Buried surface area: 2646.79 Å2
Dissociation area: 262.81 Å2
Dissociation energy (ΔGdiss): -4.42 kcal/mol
Dissociation entropy (TΔSdiss): 3.97 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-169863
Assembly 2 (preferred)
Download    3D Visualisation
Assembly Name: Peroxisome proliferator-activated receptor delta
hide full assembly name
Multimeric state: monomeric
Accessible surface area: 12282.48 Å2
Buried surface area: 2372.25 Å2
Dissociation area: 258.58 Å2
Dissociation energy (ΔGdiss): -4.96 kcal/mol
Dissociation entropy (TΔSdiss): 3.98 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-169863

Macromolecules

Peroxisome proliferator-activated receptor delta
Chains: A, B
Length: 272 amino acids
Theoretical weight: 31.11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q03181 (Residues: 170-441; Coverage: 62%)
Gene names: NR1C2, PPARB, PPARD
Pfam: Ligand-binding domain of nuclear hormone receptor
InterPro:
CATH: Retinoid X Receptor
SCOP: Nuclear receptor ligand-binding domain
Peroxisome proliferator-activated receptor delta in PDB entry 1y0s, assembly 2, front view.
Peroxisome proliferator-activated receptor delta in PDB entry 1y0s, assembly 2, side view.
Peroxisome proliferator-activated receptor delta in PDB entry 1y0s, assembly 2, top view.
Molecule details ›

Search similar proteins

Quick links