› 1xz1

X-ray diffraction
1.75Å resolution

Complex of halothane with apoferritin

Released:
DOI: 10.2210/pdb1xz1/pdb
PDB entry 1xz1 coloured by chain, front view.
PDB entry 1xz1 coloured by chain, side view.
PDB entry 1xz1 coloured by chain, top view.
Source organism: Equus caballus
Primary publication:
Structural basis for high-affinity volatile anesthetic binding in a natural 4-helix bundle protein.
Liu R, Loll PJ, Eckenhoff RG
FASEB J 19 567-76 (2005)
PMID: 15791007

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo 24-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136237 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ferritin light chain Chain: A
Molecule details ›
Chain: A
Length: 174 amino acids
Theoretical weight: 19.87 KDa
Source organism: Equus caballus
UniProt:
  • Canonical: P02791 (Residues: 2-175; Coverage: 99%)
Gene name: FTL
Sequence domains: Ferritin-like domain
Structure domains: Ferritin

Ligands and Environments

2 bound ligands:
Ligand CD 6 x CD
Ligand HLT 1 x HLT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X8C
Spacegroup: F432
Unit cell:
a: 181.61Å b: 181.61Å c: 181.61Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.181 0.179 0.212

Quick links

Citations

6 review citations

Halogen bonding in halocarbon-protein complexes: a structural survey.
Parisini et al. (2011)
5 more

6 mentions without citation

Cl-pi interactions in protein-ligand complexes.
Imai et al. (2008)
5 more