Structure analysis

X-RAY CRYSTALLOGRAPHIC STRUCTURES OF D-XYLOSE ISOMERASE-SUBSTRATE COMPLEXES POSITION THE SUBSTRATE AND PROVIDE EVIDENCE FOR METAL MOVEMENT DURING CATALYSIS

X-ray diffraction
1.96Å resolution
Assembly composition:
homo tetramer (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
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Multimeric state: homo tetramer
Accessible surface area: 45617.26 Å2
Buried surface area: 33109.3 Å2
Dissociation area: 12,429.17 Å2
Dissociation energy (ΔGdiss): 168.06 kcal/mol
Dissociation entropy (TΔSdiss): 18.12 kcal/mol
Symmetry number: 4
PDBe Complex ID: PDB-CPX-147411

Macromolecules

Chains: A, B
Length: 386 amino acids
Theoretical weight: 42.84 KDa
Source organism: Streptomyces olivochromogenes
Expression system: Not provided
UniProt:
  • Canonical: P15587 (Residues: 2-387; Coverage: 100%)
Gene name: xylA
Pfam: Xylose isomerase-like TIM barrel
InterPro:
CATH: Divalent-metal-dependent TIM barrel enzymes
SCOP: Xylose isomerase

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