1xvt Summary


Crystal Structure of Native CaiB in complex with coenzyme A

The structure was published by Rangarajan, E.S., Li, Y., Iannuzzi, P., Cygler, M., and Matte, A., in 2005 in a paper entitled "Crystal Structure of Escherichia coli Crotonobetainyl-CoA: Carnitine CoA-Transferase (CaiB) and Its Complexes with CoA and Carnitinyl-CoA." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.3 Å and deposited in 2004.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of Crotonobetainyl-CoA:carnitine CoA-transferase. This molecule has the UniProt identifier P31572 (CAIB_ECOLI)search. The sample contained 408 residues which is 100% of the natural sequence. Out of 408 residues 389 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms homodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Crotonobetainyl-CoA:carnitine CoA-transferase P31572 (1-405) (CAIB_ECOLI)search Escherichia coli K-12search 100% 408 98%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P31572 (1 - 405) Crotonobetainyl-CoA:carnitine CoA-transferase Escherichia coli

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P31572) CoA-transferase family III (CaiB/BaiF)search Crotonobetainyl-coa:carnitine coa-transferase; domain 1search, formyl-coa transferase, domain 3search PF02515: CoA-transferase family IIIsearch

Chain ID Molecular function (GO) Cellular component (GO) Biological process (GO)
A (P31572) transferase activity, transferring sulfur-containing groupssearch transferase activitysearch catalytic activitysearch carnitine dehydratase activitysearch CoA-transferase activitysearch cytoplasmsearch carnitine metabolic processsearch carnitine catabolic processsearch

Chain InterPro annotation
A CoA-transferase family IIIsearch CoA-transferase family III, crotonobetainyl-CoA:carnitine CoA-transferase CaiBsearch CoA-transferase family III domainsearch