1xva Summary



The structure was published by Fu, Z., Hu, Y., Konishi, K., et al., Gomi, T., Fujioka, M., and Takusagawa, F., in 1996 in a paper entitled "Crystal structure of glycine N-methyltransferase from rat liver." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.2 Å and deposited in 1996.

The experimental data on which the structure is based was not deposited.

This PDB entry contains multiple copies of the structure of GLYCINE N-METHYLTRANSFERASE.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms homotetramers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A GLYCINE N-METHYLTRANSFERASE P13255 (2-293) (GNMT_RAT)search Rattus norvegicussearch 100% 292 100%
B GLYCINE N-METHYLTRANSFERASE P13255 (2-293) (GNMT_RAT)search Rattus norvegicussearch 100% 292 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P13255 (2 - 293) GLYCINE N-METHYLTRANSFERASE Escherichia coli

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B (P13255) Glycine N-methyltransferasesearch Glycine N-methyltransferase, chain A, domain 1search, Vaccinia Virus protein VP39search PF12847: Methyltransferase domainsearch

Chain ID Molecular function (GO) Biological process (GO) Cellular component (GO)
A, B (P13255) glycine N-methyltransferase activitysearch folic acid bindingsearch glycine bindingsearch methyltransferase activitysearch transferase activitysearch S-adenosylmethionine-dependent methyltransferase activitysearch folic acid metabolic processsearch S-adenosylmethionine metabolic processsearch S-adenosylhomocysteine metabolic processsearch glycine metabolic processsearch sarcosine metabolic processsearch methylationsearch protein homotetramerizationsearch protein tetramerizationsearch cytoplasmsearch cytosolsearch nucleussearch

Chain InterPro annotation
A, B Glycine/Sarcosine N-methyltransferasesearch S-adenosyl-L-methionine-dependent methyltransferase-likesearch