1xtn Summary


crystal structure of CISK-PX domain with sulfates

The structure was published by Xing, Y., Liu, D, Zhang, R., Joachimiak, A., Songyang, Z., and Xu, W., in 2004 in a paper entitled "Structural basis of membrane targeting by the Phox homology domain of cytokine-independent survival kinase (CISK-PX)" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.2 Å and deposited in 2004.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of Serine/threonine-protein kinase Sgk3.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Serine/threonine-protein kinase Sgk3 Q9ERE3 (7-126) (SGK3_MOUSE)search Mus musculussearch < 90% 120 94%
B Serine/threonine-protein kinase Sgk3 Q9ERE3 (7-126) (SGK3_MOUSE)search Mus musculussearch < 90% 120 94%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q9ERE3 (7 - 126) Serine/threonine-protein kinase Sgk3 Mus musculus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B PX domainsearch PX Domainsearch PX domainsearch

Chain ID Molecular function (GO)
A, B (Q9ERE3) phosphatidylinositol bindingsearch

Chain InterPro annotation
A, B Phox homologous domainsearch