Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:
Structure analysis Details
Assembly composition:
hetero heptamer (preferred)
Assembly name:
Cholera toxin (preferred)
PDBe Complex ID:
PDB-CPX-134377 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Cholera enterotoxin subunit A1
Molecule details ›
Chain: A
Length: 194 amino acids
Theoretical weight: 21.84 KDa
Source organism: Vibrio cholerae 569B
UniProt:
Sequence domains: Heat-labile enterotoxin alpha chain
Structure domains: Heat-Labile Enterotoxin, subunit A
Length: 194 amino acids
Theoretical weight: 21.84 KDa
Source organism: Vibrio cholerae 569B
UniProt:
- Canonical:
P01555 (Residues: 19-212; Coverage: 81%)
Sequence domains: Heat-labile enterotoxin alpha chain
Structure domains: Heat-Labile Enterotoxin, subunit A
Cholera enterotoxin subunit A2
Molecule details ›
Chain: C
Length: 46 amino acids
Theoretical weight: 5.4 KDa
Source organism: Vibrio cholerae 569B
UniProt:
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Length: 46 amino acids
Theoretical weight: 5.4 KDa
Source organism: Vibrio cholerae 569B
UniProt:
- Canonical: P01555 (Residues: 213-258; Coverage: 19%)
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Cholera enterotoxin subunit B
Molecule details ›
Chains: D, E, F, G, H
Length: 103 amino acids
Theoretical weight: 11.69 KDa
Source organism: Vibrio cholerae 569B
UniProt:
Sequence domains: Heat-labile enterotoxin beta chain
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Length: 103 amino acids
Theoretical weight: 11.69 KDa
Source organism: Vibrio cholerae 569B
UniProt:
- Canonical: P01556 (Residues: 22-124; Coverage: 100%)
Sequence domains: Heat-labile enterotoxin beta chain
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Spacegroup:
P21
