spacer
EBI PDBe PDBeView

PDBe Entry: 1xr2 view

Crystal Structure of oxidized T. maritima Cobalamin-Independent Methionine Synthase complexed with Methyltetrahydrofolate
Summary
Header TRANSFERASEsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 2.35 Å, R-factor: 20.7%, Free R-factor: 25.4%, Spacegroup: P 21 21 2
Released 01/03/2005, deposition: 13/10/2004, last revision: 24/02/2009
Authors Pejchal, R.search; Ludwig, M.L.search
Primary citation Cobalamin-independent methionine synthase (MetE): a face-to-face double barrel that evolved by gene duplication
PLOS BIOL.search vol:3, pag:e31 (2005) [PubMed ID 15630480 ]search
Keywords TIM barrelsearch, zincsearch, homocysteinesearch, methyltetrahydrofolatesearch, TRANSFERASEsearch
EC 2.1.1.14 ExPASy BRENDA search (A B)
Organism Thermotoga maritima 2336search(A B)
UniProt 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14) (Methionine synthase, vitamin-B12 independent isozyme) (Cobalamin-independent methionine synthase) Q9X112search (A B)
Solvent A, B
Related entries 1t7l, 1xdj, 1xpg
Polymers
Id Name Type UniProt Residues Observed
A, B 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase Protein Q9X112 (METE_THEMA)search
 766 95%
Heterogens
Id Name Ligands
A, B SULFATE ION SO4 search
A, B 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID C2F search
B, A MESO-ERYTHRITOL MRY search
spacer