1xlb Summary

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MECHANISM FOR ALDOSE-KETOSE INTERCONVERSION BY D-XYLOSE ISOMERASE INVOLVING RING OPENING FOLLOWED BY A 1,2-HYDRIDE SHIFT

The structure was published by Collyer, C.A., Henrick, K., and Blow, D.M., in 1990 in a paper entitled "Mechanism for aldose-ketose interconversion by D-xylose isomerase involving ring opening followed by a 1,2-hydride shift." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.5 Å and deposited in 1991.

The experimental data on which the structure is based was not deposited.

This PDB entry contains multiple copies of the structure of D-XYLOSE ISOMERASE.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms homotetramers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A D-XYLOSE ISOMERASE P12070 (2-395) (XYLA_ARTS7)search Arthrobacter sp. NRRL B3728search 99% 394 99%
B D-XYLOSE ISOMERASE P12070 (2-395) (XYLA_ARTS7)search Arthrobacter sp. NRRL B3728search 99% 394 99%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P12070 (2 - 395) D-XYLOSE ISOMERASE Arthrobacter sp. NRRL B3728

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B (P12070) Xylose isomerasesearch Divalent-metal-dependent TIM barrel enzymessearch PF01261: Xylose isomerase-like TIM barrelsearch

Chain ID Biological process (GO) Cellular component (GO) Molecular function (GO)
A, B (P12070) pentose-phosphate shuntsearch carbohydrate metabolic processsearch D-xylose metabolic processsearch cytoplasmsearch xylose isomerase activitysearch metal ion bindingsearch magnesium ion bindingsearch isomerase activitysearch

Chain InterPro annotation
A, B Xylose isomerasesearch Xylose isomerase-like, TIM barrel domainsearch Xylose isomerase, actinobacteriasearch