› 1xie

X-ray diffraction
1.7Å resolution

MODES OF BINDING SUBSTRATES AND THEIR ANALOGUES TO THE ENZYME D-XYLOSE ISOMERASE

Released:
DOI: 10.2210/pdb1xie/pdb
PDB entry 1xie coloured by chain, front view.
PDB entry 1xie coloured by chain, side view.
PDB entry 1xie coloured by chain, top view.
Source organism: Streptomyces rubiginosus
Primary publication:
Modes of binding substrates and their analogues to the enzyme D-xylose isomerase.
Carrell HL, Hoier H, Glusker JP
Acta Crystallogr D Biol Crystallogr 50 113-23 (1994)
PMID: 15299449

Function and Biology Details

Reaction catalysed: 
Alpha-D-xylopyranose = alpha-D-xylufuranose
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150204 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Xylose isomerase Chain: A
Molecule details ›
Chain: A
Length: 388 amino acids
Theoretical weight: 43.25 KDa
Source organism: Streptomyces rubiginosus
Expression system: Not provided
UniProt:
  • Canonical: P24300 (Residues: 1-388; Coverage: 100%)
Gene name: xylA
Sequence domains: Xylose isomerase-like TIM barrel
Structure domains: Divalent-metal-dependent TIM barrel enzymes

Ligands and Environments

2 bound ligands:
Ligand ASO 1 x ASO
Ligand MN 2 x MN
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: I222
Unit cell:
a: 93.5Å b: 99.56Å c: 102.8Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.162 not available not available
Expression system: Not provided

Quick links

Citations

1 review citation

Molecular and industrial aspects of glucose isomerase.
Bhosale et al. (1996)
14 other articles

4 mentions without citation

Multiple structural alignment by secondary structures: algorithm and applications.
Dror et al. (2003)
3 more