Crystal Structures of Protein Kinase B Selective Inhibitors in Complex with Protein Kinase A and Mutants
The structure was published by Breitenlechner, C.B., Friebe, W.-G., Brunet, E., et al., Huber, R., Engh, R.A., and Masjost, B., in 2005 in a paper entitled "Design and crystal structures of protein kinase B-selective inhibitors in complex with protein kinase A and mutants" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.46 Å and deposited in 2004.
The experimental data on which the structure is based was not deposited.
This PDB entry contains a complex of 2 biomacromolecules, namely cAMP-dependent protein kinase, alpha-catalytic subunit and cAMP-dependent protein kinase inhibitor, alpha form.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 2 unique UniProt proteins: