1xgm Summary



The structure was published by Tahirov, T.H., Oki, H., Tsukihara, T., et al., Izu, Y., Tsunasawa, S., and Kato, I., in 1998 in a paper entitled "Crystal structure of methionine aminopeptidase from hyperthermophile, Pyrococcus furiosus." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.8 Å and deposited in 1997.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of METHIONINE AMINOPEPTIDASE.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms homodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A METHIONINE AMINOPEPTIDASE P56218 (1-295) (MAP2_PYRFU)search Pyrococcus furiosus DSM 3638search 99% 295 100%
B METHIONINE AMINOPEPTIDASE P56218 (1-295) (MAP2_PYRFU)search Pyrococcus furiosus DSM 3638search 99% 295 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P56218 (1 - 295) METHIONINE AMINOPEPTIDASE Pyrococcus furiosus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B (P56218) Methionine aminopeptidase, insert domainsearch, Creatinase/aminopeptidasesearch Creatinase/methionine aminopeptidase superfamilysearch, "winged helix" repressor DNA binding domainsearch PF00557: Metallopeptidase family M24search

Chain ID Molecular function (GO) Biological process (GO)
A, B (P56218) aminopeptidase activitysearch metalloaminopeptidase activitysearch peptidase activitysearch metal ion bindingsearch metalloexopeptidase activitysearch hydrolase activitysearch proteolysissearch protein initiator methionine removalsearch

Chain InterPro annotation
A, B Peptidase M24, structural domainsearch Peptidase M24, methionine aminopeptidasesearch Peptidase M24A, methionine aminopeptidase, subfamily 2search Winged helix-turn-helix DNA-binding domainsearch Peptidase M24A, methionine aminopeptidase, subfamily 2, binding sitesearch Methionine aminopeptidase, archaealsearch