1x8o Summary


1.01 A Crystal Structure Of Nitrophorin 4 From Rhodnius Prolixus Complexed With Nitric Oxide at pH 5.6

The structure was published by Kondrashov, D.A., Roberts, S.A., Weichsel, A., and Montfort, W.R., in 2004 in a paper entitled "Protein functional cycle viewed at atomic resolution: conformational change and mobility in nitrophorin 4 as a function of pH and NO binding" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.01 Å and deposited in 2004.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of Nitrophorin 4. This molecule has the UniProt identifier Q94734 (NP4_RHOPR)search. The sample contained 184 residues which is 100% of the natural sequence. Out of 184 residues 184 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Nitrophorin 4 Q94734 (22-205) (NP4_RHOPR)search Rhodnius prolixussearch 100% 184 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q94734 (22 - 205) Nitrophorin 4 Rhodnius prolixus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (Q94734) Retinol binding protein-likesearch Lipocalinsearch PF02087: Nitrophorinsearch

Chain ID Molecular function (GO) Biological process (GO) Cellular component (GO)
A (Q94734) histamine bindingsearch nitric oxide bindingsearch metal ion bindingsearch oxidoreductase activitysearch oxidation-reduction processsearch regulation of blood vessel sizesearch vasodilationsearch extracellular regionsearch

Chain InterPro annotation
A Nitrophorin domainsearch Calycin-likesearch Calycinsearch Nitrophorinsearch