1x6h Summary

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Solution structures of the C2H2 type zinc finger domain of human Transcriptional repressor CTCF

A publication describing this structure is not available. The depositing authors are Sato, M.search; Saito, K.search; Koshiba, S.search; Inoue, M.search; Kigawa, T.search; Yokoyama, S.search; RIKEN Structural Genomics/Proteomics Initiative (RSGI)search

The structure was determined using NMR spectroscopy and deposited in 2005.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of Transcriptional repressor CTCF. This molecule has the UniProt identifier P49711 (CTCF_HUMAN)search. The sample contained 86 residues which is < 90% of the natural sequence. Out of 86 residues 86 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Transcriptional repressor CTCF P49711 (515-587) (CTCF_HUMAN)search Homo sapienssearch < 90% 86 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P49711 (515 - 587) Transcriptional repressor CTCF Homo sapiens

Chain Structural classification (SCOP) Sequence family (Pfam)
A Classic zinc finger, C2H2search Zinc-finger double domainsearch, C2H2-type zinc fingersearch

Chain ID Molecular function (GO)
A (P49711) metal ion bindingsearch nucleic acid bindingsearch

Chain InterPro annotation
A Zinc finger, C2H2search Zinc finger C2H2-type/integrase DNA-binding domainsearch Zinc finger, C2H2-likesearch