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PDBe Entry: 1wxz 
Crystal structure of adenosine deaminase ligated with a potent inhibitor
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HYDROLASE
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X-RAY DIFFRACTION
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Resolution: 2.8 Å, R-factor: 22.0%, Free R-factor: 22.3%, Spacegroup: P 43 21 2
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16/08/2005, deposition: 02/02/2005, last revision: 24/02/2009
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Kinoshita, T.
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Rational design of non-nucleoside, potent, and orally bioavailable adenosine deaminase inhibitors: predicting enzyme conformational change and metabolism
J.MED.CHEM. vol:48, pag:4750-4753 (2005) [PubMed ID 16033254 ]
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beta barel, HYDROLASE
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3.5.4.4 ExPASy BRENDA (A)
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Bos taurus(cattle) 9913(A)
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Adenosine deaminase (EC 3.5.4.4) (Adenosine aminohydrolase) P56658 (A)
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A
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| A |
Adenosine deaminase |
Protein |
P56658 (ADA_BOVIN)
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356 |
98% |
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| A |
ZINC ION |
ZN
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| A |
1-((1R,2S)-1-{2-[2-(4-CHLOROPHENYL)-1,3-BENZOXAZOL-7-YL]ETHYL}-2-HYDROXYPROPYL)-1H-IMIDAZOLE-4-CARBOXAMIDE |
FRL
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