› 1wvw

X-ray diffraction
2.4Å resolution

Crystal structures of kinase domain of DAP kinase in complex with small molecular inhibitors

Released:
DOI: 10.2210/pdb1wvw/pdb
PDB entry 1wvw coloured by chain, front view.
PDB entry 1wvw coloured by chain, side view.
PDB entry 1wvw coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Ueda Y, Ogata H, Yamakawa A, Higuchi Y

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156788 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Death-associated protein kinase 1 Chain: A
Molecule details ›
Chain: A
Length: 278 amino acids
Theoretical weight: 31.98 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P53355 (Residues: 1-278; Coverage: 19%)
Gene names: DAPK, DAPK1
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL40B2
Spacegroup: P212121
Unit cell:
a: 77.992Å b: 109.909Å c: 50.063Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.232 0.232 0.27
Expression system: Escherichia coli BL21(DE3)

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