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EBI PDBe PDBeView

PDBe Entry: 1wdk view

fatty acid beta-oxidation multienzyme complex from Pseudomonas fragi, form I (native2)
Summary
Header LYASE,OXIDOREDUCTASE/TRANSFERASEsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 2.5 Å, R-factor: 20.56%, Free R-factor: 24.43%, Spacegroup: C 1 2 1
Released 27/07/2004, deposition: 17/05/2004, last revision: 24/02/2009
Authors Ishikawa, M.search; Tsuchiya, D.search; Oyama, T.search; Tsunaka, Y.search; Morikawa, K.search
Primary citation Structural basis for channelling mechanism of a fatty acid beta-oxidation multienzyme complex
EMBO J.search vol:23, pag:2745-2754 (2004) [PubMed ID 15229654 ]search
Keywords alpha2beta2 heterotetrameric complexsearch, LYASEsearch, OXIDOREDUCTASE/TRANSFERASE COMPLEXsearch, LYASEsearch, OXIDOREDUCTASE/TRANSFERASE COMPLEXsearch
EC 1.1.1.35 ExPASy BRENDA search 4.2.1.17 ExPASy BRENDA search 5.1.2.3 ExPASy BRENDA search 5.3.3.8 ExPASy BRENDA search (A B), 2.3.1.16 ExPASy BRENDA search (C D)
Organism Pseudomonas fragi 296search(A B C D)
UniProt Fatty acid oxidation complex subunit alpha [Includes: Enoyl-CoA hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA isomerase/3-hydroxybutyryl-CoA epimerase (EC 4.2.1.17) (EC 5.3.3.8) (EC 5.1.2.3); 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35)] P28793search (A B)
3-ketoacyl-CoA thiolase (EC 2.3.1.16) (Fatty acid oxidation complex subunit beta) (Beta-ketothiolase) (Acetyl-CoA acyltransferase) P28790search (C D)
Solvent A, B, C, D
Related entries 1wdl, 1wdm
Polymers
Id Name Type UniProt Residues Observed
A, B Fatty oxidation complex alpha subunit Protein P28793 (FADB_PSEFR)search
 715 99%
C, D 3-ketoacyl-CoA thiolase Protein P28790 (FADA_PSEFR)search
 390 100%
Heterogens
Id Name Ligands
D, C MERCURY (II) ION HG search
A ZINC ION ZN search
C, D ACETYL COENZYME *A ACO search
A, B NICOTINAMIDE-ADENINE-DINUCLEOTIDE NAD search
A, B 3,6,9,12,15-PENTAOXATRICOSAN-1-OL N8E search
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