ACTIVE SITE THROMBIN INHIBITORS
The structure was published by Hartshorn, M.J., Murray, C.W., Cleasby, A., Frederickson, M., Tickle, I.J., and Jhoti, H., in 2005 in a paper entitled "Fragment-Based Lead Discovery Using X-Ray Crystallography" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.2 Å and deposited in 2004.
The experimental data on which the structure is based was not deposited.
This PDB entry contains a complex of 3 biomacromolecules, namely THROMBIN LIGHT CHAIN, THROMBIN HEAVY CHAIN, and HIRUGEN.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule most likely forms heterotrimers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 3 unique UniProt proteins: