CO-CRYSTAL STRUCTURE OF 6-CYCLOHEXYLMETHOXY-8-ISOPROPYL-9H-PURIN-2- YLAMINE AND MONOMERIC CDK2
The structure was published by Carbain, B., Paterson, D.J., Anscombe, E., et al., Roche, C., Wang, L., and Griffin, R.J., in 2014 in a paper entitled "8-Substituted O6-Cyclohexylmethylguanine Cdk2 Inhibitors; Using Structure-Based Inhibitor Design to Optimise an Alternative Binding Mode." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.05 Å and deposited in 2004.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of CELL DIVISION PROTEIN KINASE 2.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule is most likely monomeric.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: