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EBI PDBe PDBeView

PDBe Entry: 1w0t view

HTRF1 DNA-BINDING DOMAIN IN COMPLEX WITH TELOMERIC DNA.
Summary
Header DNA-BINDING PROTEINsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 2.0 Å, R-factor: 25.2%, Free R-factor: 27.3%, Spacegroup: P 21 21 21
Released 22/12/2004, deposition: 11/06/2004, last revision: 09/06/2009
Authors Court, R.I.search; Chapman, L.M.search; Fairall, L.search; Rhodes, D.search
Primary citation How the Human Telomeric Proteins Trf1 and Trf2 Recognize Telomeric DNA: A View from High-Resolution Crystal Structures
EMBO REP.search vol:6, pag:39-45 (2005) [PubMed ID 15608617 ]search
Keywords TELOMEREsearch, DNA-BINDING PROTEINsearch, HOMEODOMAINsearch, MITOSISsearch, CELL CYCLEsearch, NUCLEAR PROTEINsearch, CHROMOSOMAL PROTEINsearch, PHOSPHORYLATIONsearch, ADP-RIBOSYLATIONsearch
Organism Homo sapiens(human) 9606search(A B)
UniProt Telomeric repeat-binding factor 1 (TTAGGG repeat-binding factor 1) (NIMA-interacting protein 2) (Telomeric protein Pin2/TRF1) P54274search (A B)
Solvent A, B, C, D
Related entries 1ba5, 1h6o, 1ity, 1iv6, 1w0u
Polymers
Id Name Type UniProt Residues Observed
A, B TELOMERIC REPEAT BINDING FACTOR 1 Protein P54274 (TERF1_HUMAN)search
 53 98%
C 5'-D(*CP*TP*GP*TP*TP*AP*GP*GP*GP*TP *TP*AP*GP*GP*GP*TP*TP*AP*G)-3' DNA
19 100%
D 5'-D(*TP*CP*TP*AP*AP*CP*CP*CP*TP*AP *AP*CP*CP*CP*TP*AP*AP*CP*A)-3' DNA
19 100%
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