› 1vtx

Solution NMR

DELTA-ATRACOTOXIN-HV1 (VERSUTOXIN) FROM HADRONYCHE VERSUTA, NMR, 20 STRUCTURES

Released:
DOI: 10.2210/pdb1vtx/pdb
PDB entry 1vtx coloured by chain, ensemble of 20 models, front view.
PDB entry 1vtx coloured by chain, ensemble of 20 models, side view.
PDB entry 1vtx coloured by chain, ensemble of 20 models, top view.
Source organism: Hadronyche versuta
Primary publication:
The structure of versutoxin (delta-atracotoxin-Hv1) provides insights into the binding of site 3 neurotoxins to the voltage-gated sodium channel.
Fletcher JI, Chapman BE, Mackay JP, Howden ME, King GF
Structure 5 1525-35 (1997)
PMID: 9384567

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146608 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Delta-hexatoxin-Hv1a Chain: A
Molecule details ›
Chain: A
Length: 42 amino acids
Theoretical weight: 4.86 KDa
Source organism: Hadronyche versuta
UniProt:
  • Canonical: P13494 (Residues: 1-42; Coverage: 100%)
Sequence domains: Delta Atracotoxin
Structure domains: Omega-AgatoxinV

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: DISTANCE GEOMETRY AND DYNAMICAL SIMULATED ANNEALING

Quick links

Citations

21 review citations

The cystine knot motif in toxins and implications for drug design.
Craik et al. (2001)
20 more

5 mentions without citation

Structure and sodium channel activity of an excitatory I1-superfamily conotoxin.
Buczek et al. (2007)
4 more