› 1vrd

X-ray diffraction
2.18Å resolution

Crystal structure of Inosine-5'-monophosphate dehydrogenase (TM1347) from THERMOTOGA MARITIMA at 2.18 A resolution

Released:
DOI: 10.2210/pdb1vrd/pdb
PDB entry 1vrd coloured by chain, front view.
PDB entry 1vrd coloured by chain, side view.
PDB entry 1vrd coloured by chain, top view.
Source organism: Thermotoga maritima MSB8
Entry author: Joint Center for Structural Genomics (JCSG)

Function and Biology Details

Reaction catalysed: 
Inosine 5'-phosphate + NAD(+) + H(2)O = xanthosine 5'-phosphate + NADH
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194766 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Inosine-5'-monophosphate dehydrogenase Chains: A, B
Molecule details ›
Chains: A, B
Length: 494 amino acids
Theoretical weight: 53.55 KDa
Source organism: Thermotoga maritima MSB8
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9X168 (Residues: 1-482; Coverage: 100%)
Gene names: TM_1347, guaB
Sequence domains:
Structure domains: Aldolase class I

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.3
Spacegroup: I4
Unit cell:
a: 120.083Å b: 120.083Å c: 144.079Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.219 0.217 0.258
Expression system: Escherichia coli

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