1vlh Summary

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Crystal structure of Phosphopantetheine adenylyltransferase (TM0741) from Thermotoga maritima at 2.20 A resolution

The structure was published by Joint Center for Structural Genomics (JCSG), in in a paper entitled "Crystal structure of Phosphopantetheine adenylyltransferase (TM0741) from Thermotoga maritima at 2.20 A resolution" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.2 Å and deposited in 2004.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of Phosphopantetheine adenylyltransferase.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms homohexamers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Phosphopantetheine adenylyltransferase Q9WZK0 (1-161) (COAD_THEMA)search Thermotoga maritima MSB8search 100% 173 91%
B Phosphopantetheine adenylyltransferase Q9WZK0 (1-161) (COAD_THEMA)search Thermotoga maritima MSB8search 100% 173 91%
C Phosphopantetheine adenylyltransferase Q9WZK0 (1-161) (COAD_THEMA)search Thermotoga maritima MSB8search 100% 173 91%
D Phosphopantetheine adenylyltransferase Q9WZK0 (1-161) (COAD_THEMA)search Thermotoga maritima MSB8search 100% 173 91%
E Phosphopantetheine adenylyltransferase Q9WZK0 (1-161) (COAD_THEMA)search Thermotoga maritima MSB8search 100% 173 91%
F Phosphopantetheine adenylyltransferase Q9WZK0 (1-161) (COAD_THEMA)search Thermotoga maritima MSB8search 100% 173 91%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q9WZK0 (1 - 161) Phosphopantetheine adenylyltransferase Thermotoga maritima

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B, C, D, E, F (Q9WZK0) Adenylyltransferasesearch HUPssearch PF01467: Cytidylyltransferasesearch

Chain ID Molecular function (GO) Cellular component (GO) Biological process (GO)
A, B, C, D, E, F (Q9WZK0) pantetheine-phosphate adenylyltransferase activitysearch transferase activitysearch ATP bindingsearch nucleotidyltransferase activitysearch nucleotide bindingsearch catalytic activitysearch cytoplasmsearch coenzyme A biosynthetic processsearch biosynthetic processsearch

Chain InterPro annotation
A, B, C, D, E, F Coenzyme A biosynthesis proteinsearch Cytidyltransferase-like domainsearch Rossmann-like alpha/beta/alpha sandwich foldsearch