1va2 Summary


Solution Structure of Transcription Factor Sp1 DNA Binding Domain (Zinc Finger 2)

The structure was published by Oka, S., Shiraishi, Y., Yoshida, T., Ohkubo, T., Sugiura, Y., and Kobayashi, Y., in 2004 in a paper entitled "NMR structure of transcription factor Sp1 DNA binding domain" (abstract).

The structure was determined using NMR spectroscopy and deposited in 2004.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of Transcription factor Sp1. This molecule has the UniProt identifier P08047 (SP1_HUMAN)search. The sample contained 31 residues which is < 90% of the natural sequence. Out of 31 residues 31 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Transcription factor Sp1 P08047 (654-684) (SP1_HUMAN)search Homo sapienssearch < 90% 31 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P08047 (654 - 684) Transcription factor Sp1 Homo sapiens

Chain Structural classification (SCOP) Sequence family (Pfam)
A Classic zinc finger, C2H2search Zinc-finger double domainsearch

Chain ID Molecular function (GO)
A (P08047) nucleic acid bindingsearch metal ion bindingsearch

Chain InterPro annotation
A Zinc finger, C2H2search Zinc finger C2H2-type/integrase DNA-binding domainsearch Zinc finger, C2H2-likesearch