1v74 Summary

pdbe.org/1v74
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ribonuclease-inhibitor complex

The structure was published by Graille, M., Mora, L., Buckingham, R.H., Van Tilbeurgh, H., and De Zamaroczy, M., in 2004 in a paper entitled "Structural inhibition of the colicin D tRNase by the tRNA-mimicking immunity protein" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.0 Å and deposited in 2003.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely Colicin D and Colicin D immunity protein.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms heterodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Colicin D P17998 (591-697) (CEAD_ECOLX)search Escherichia colisearch < 90% 107 100%
B Colicin D immunity protein P11899 (1-87) (IMMD_ECOLX)search Escherichia colisearch 99% 87 100%


This entry contains 2 unique UniProt proteins:

UniProt accession Name Organism PDB
P17998 (591 - 697) Colicin D Escherichia coli
P11899 (1 - 87) Colicin D immunity protein Escherichia coli

Chain Structural classification (SCOP) Sequence family (Pfam)
A Colicin D nuclease domainsearch Colicin Dsearch
B (P11899) Colicin D immunity proteinsearch PF09204: Bacterial self-protective colicin-like immunitysearch

Chain ID Molecular function (GO) Biological process (GO)
A (P17998) ribonuclease activitysearch
B (P11899) toxic substance bindingsearch protein bindingsearch bacteriocin immunitysearch

Chain InterPro annotation
A Colicin D C-terminalsearch
B Colicin D immunity protein domainsearch