1uus Summary

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STRUCTURE OF AN ACTIVATED DICTYOSTELIUM STAT IN ITS DNA-UNBOUND FORM

The structure was published by Soler-Lopez, M., Petosa, C., Fukuzawa, M., Ravelli, R., Williams, J.G., and Muller, C.W., in 2004 in a paper entitled "Structure of an Activated Dictyostelium Stat in its DNA-Unbound Form" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.8 Å and deposited in 2004.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of STAT PROTEIN. This molecule has the UniProt identifier O00910 (STATA_DICDI)search. The sample contained 473 residues which is < 90% of the natural sequence. Out of 473 residues 462 were observed and are deposited in the PDB.

The molecule most likely forms homodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A STAT PROTEIN O00910 (235-707) (STATA_DICDI)search Dictyostelium discoideumsearch < 90% 473 98%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
O00910 (235 - 707) STAT PROTEIN Dictyostelium discoideum

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A STATsearch, STAT DNA-binding domainsearch, SH2 domainsearch STAT; domain 1search, Immunoglobulin-likesearch, EF-handsearch, SHC Adaptor Proteinsearch SH2 domainsearch, Dictyostelium STAT, coiled coilsearch

Chain ID Cellular component (GO) Molecular function (GO) Biological process (GO)
A (O00910) nucleussearch sequence-specific DNA binding transcription factor activitysearch calcium ion bindingsearch signal transducer activitysearch regulation of transcription, DNA-templatedsearch signal transductionsearch

Chain InterPro annotation
A SH2 domainsearch Transcription factor STATsearch p53-like transcription factor, DNA-bindingsearch Rel homology domainsearch EF-hand domain pairsearch STAT transcription factor homologue, coiled coilsearch STAT transcription factor, coiled coilsearch