Cyclin A binding groove inhibitor Ace-Arg-Lys-Leu-Phe-Gly
The structure was published by Andrews, M., Mcinnes, C., Kontopidis, G., et al., Cowan, A., Plater, A., and Fischer, P., in 2004 in a paper entitled "Design, Synthesis, Biological Activity and Structural Analysis of Cyclic Peptide Inhibitors Targeting the Substrate Recruitment Site of Cyclin-Dependent Kinase Complexes" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.6 Å and deposited in 2003.
The experimental data on which the structure is based was also deposited.
This PDB entry contains a complex of 3 biomacromolecules, namely CELL DIVISION PROTEIN KINASE 2, CYCLIN A2, and PEPTIDE INHIBITOR.
The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 2 unique UniProt proteins: