STRUCTURAL MECHANISM FOR THE INHIBITION OF CDK5-P25 BY ROSCOVITINE, ALOISINE AND INDIRUBIN.
The structure was published by Mapelli, M., Massimilinao, L., Crovace, C., et al., Tsai, L.-H., Meijer, L., and Musacchio, A., in 2005 in a paper entitled "Mechanism of Cdk5/P25 Binding by Cdk Inhibitors" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.3 Å and deposited in 2003.
The experimental data on which the structure is based was also deposited.
This PDB entry contains a complex of 2 biomacromolecules, namely CELL DIVISION PROTEIN KINASE 5 and CYCLIN-DEPENDENT KINASE 5 ACTIVATOR 1.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 2 unique UniProt proteins: