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PDBe Entry: 1uml 
Crystal structure of adenosine deaminase complexed with a potent inhibitor FR233624
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HYDROLASE
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X-RAY DIFFRACTION
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Resolution: 2.5 Å, R-factor: 24.0%, Free R-factor: 28.6%, Spacegroup: P 43 21 2
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21/09/2004, deposition: 03/10/2003, last revision: 24/02/2009
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Kinoshita, T.
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Structure-based design, synthesis, and structure-activity relationship studies of novel non-nucleoside adenosine deaminase inhibitors
J.MED.CHEM. vol:47, pag:3730-3743 (2004) [PubMed ID 15239652 ]
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beta barrel, zinc, HYDROLASE
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3.5.4.4 ExPASy BRENDA (A)
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Bos taurus(cattle) 9913(A)
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Adenosine deaminase (EC 3.5.4.4) (Adenosine aminohydrolase) P56658 (A)
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A
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1o5r
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| A |
Adenosine deaminase |
Protein |
P56658 (ADA_BOVIN)
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356 |
98% |
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| A |
ZINC ION |
ZN
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| A |
1-((1R)-1-(HYDROXYMETHYL)-3-{6-[(3-PHENYLPROPANOYL)AMINO]-1H-INDOL-1-YL}PROPYL)-1H-IMIDAZOLE-4-CARBOXAMIDE |
FR4
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