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PDBe Entry: 1umc 
branched-chain 2-oxo acid dehydrogenase (E1) from Thermus thermophilus HB8 with 4-methylpentanoate
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Oxidoreductase
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X-RAY DIFFRACTION
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Resolution: 2.4 Å, R-factor: 19.0%, Free R-factor: 20.6%, Spacegroup: C 2 2 21
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30/03/2004, deposition: 25/09/2003, last revision: 24/02/2009
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Nakai, T.; Nakagawa, N.; Maoka, N.; Masui, R.; Kuramitsu, S.; Kamiya, N.; RIKEN Structural Genomics/Proteomics Initiative (RSGI)
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Ligand-induced Conformational Changes and a Reaction Intermediate in Branched-chain 2-Oxo Acid Dehydrogenase (E1) from Thermus thermophilus HB8, as Revealed by X-ray Crystallography
J.MOL.BIOL. vol:337, pag:1011-1033 (2004) [PubMed ID 15033367 ]
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alpha(2)beta(2) tetramer, structural genomics, RIKEN Structural Genomics/Proteomics Initiative, RSGI, Oxidoreductase
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1.2.4.4 ExPASy BRENDA (A B C D)
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Thermus thermophilus 274(A C B D)
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2-oxoisovalerate dehydrogenase subunit alpha (EC 1.2.4.4) (Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain) (BCKDH E1-alpha) Q5SLR4 (A C)
2-oxoisovalerate dehydrogenase subunit beta (EC 1.2.4.4) (Branched-chain alpha-keto acid dehydrogenase E1 component beta chain) (BCKDH E1-beta) Q5SLR3 (B D)
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A, B, C, D
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1um9, 1umb, 1umd
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| A, C |
2-oxo acid dehydrogenase alpha subunit |
Protein |
Q5SLR4 (ODBA_THET8)
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367 |
98% |
| B, D |
2-oxo acid dehydrogenase beta subunit |
Protein |
Q5SLR3 (ODBB_THET8)
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324 |
99% |
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| A, C |
MAGNESIUM ION |
MG
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| A, C |
THIAMIN DIPHOSPHATE |
TDP
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| D |
4-METHYL VALERIC ACID |
4MV
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