APPLICATION OF CRYSTALLOGRAPHIC AND MODELING METHODS IN THE DESIGN OF PURINE NUCLEOSIDE PHOSPHORYLASE INHIBITORS
The structure was published by Ealick, S.E., Babu, Y.S., Bugg, C.E., et al., Guida, W.C., Montgomery, J.A., and Secrist 3rd., J.A., in 1991 in a paper entitled "Application of crystallographic and modeling methods in the design of purine nucleoside phosphorylase inhibitors." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.75 Å and deposited in 1991.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of PURINE NUCLEOSIDE PHOSPHORYLASE. This molecule has the UniProt identifier P00491 (PNPH_HUMAN). The sample contained 289 residues which is 100% of the natural sequence. Out of 289 residues 288 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule most likely forms homotrimers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: