Structural basis for the selective inhibition of JNK1 by the scaffolding protein JIP1 and SP600125
The structure was published by Heo, Y.-S., Kim, S.K., Seo, C.I., et al., Cho, J.M., Lee, T.G., and Yang, C.-H., in 2004 in a paper entitled "Structural basis for the selective inhibition of JNK1 by the scaffolding protein JIP1 and SP600125" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.7 Å and deposited in 2003.
The experimental data on which the structure is based was also deposited.
This PDB entry contains a complex of 2 biomacromolecules, namely mitogen-activated protein kinase 8 isoform 4 and 11-mer peptide from C-jun-amino-terminal kinase interacting protein 1.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule most likely forms heterodimers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 2 unique UniProt proteins: